Plenary and keynote speakers
Professor Lynn F Gladden, FRS, FREng, University of Cambridge, UK
Magnetic Resonance Imaging: Opportunities in Chemical Engineering Research and Practice
This presentation will discuss the many ways in which imaging and tomographic methods, and magnetic resonance imaging (MRI) in particular, can contribute to chemical engineering research and practice. Many of the examples will be taken from the world of reaction engineering but examples of how these MRI methods can be transferred to other sectors such as EOR R&D will also be shown. The presentation will be based around 3 themes:
- How can imaging aid the development and validation of simulation codes?
- What’s happening inside the ‘black box’? – examples of how imaging can help identify the correct physical mechanism upon which we can base models better able to describe chemical engineering processes
- Examples of where magnetic resonance can provide information which has, as yet, been unobtainable; for example, phase behaviour inside catalyst pellets, and direct measurements of mass transfer.
About Professor Lynn F Gladden
Lynn Gladden is the Shell Professor of Chemical Engineering at the University of Cambridge. Alongside her research interests, she is a member of Shell Science Council and the Science and Technology Advisory Council to NPL. She is also a member of the US National Academy of Engineering.
Professor David Mooney, Harvard University, USA
Building Immunity with Biomaterials
Dysfunction of the immune system underlies many diseases. However, strategies to effectively program an immune response, and reprogram undesired responses, by manipulating a patient’s immune cells are at an early stage. We are creating biomaterials capable of concentrating, interrogating, and manipulating immune cells ex vivo and in the body by controlling, in space and time, the interaction of the immune cells with immunomodulatory agents. The utility of this concept in the development of therapeutic cancer vaccines will be highlighted.
About Professor David Mooney
David Mooney is the Pinkas Family Professor at Harvard University and the Wyss Institute. He earned his PhD at MIT and BS in Chemical Engineering at the University of Wisconsin. He is a member of the National Academy of Engineering and the National Academy of Medicine.
Professor Ian Noble, Senior R&D Director, Mondelez R&D, UK
Meeting the Challenges for the Future of our Food - Engineering a More Sustainable Global Food System
Our 20th Century Industrial Food System succeeded in preparing low cost, convenient foods, where preference and cost were key drivers. The new challenges ahead of us are far more complex. Now we must address sustainable uses of raw materials and energy, together with new targets for consumer needs, which include long term health as well as short term pleasure. Success will depend on meeting the aspiration of consumers to be both delighted and well nourished, whilst re-assuring them of their future well-being – posing new questions and challenges.
Professor Nigel Brandon, FREng, Imperial College
Electrochemical Engineering for Energy Applications
The presentation will discuss the need for innovation in the way we produce and use energy, and the role that electrochemical technologies can play in enabling the transition to a lower carbon energy system. The presentation will draw on the authors own experience of developing fuel cell, hydrogen and energy storage technologies to show the increasing opportunity for electrochemical technologies in the energy sector, and in turn the growing need for electrochemical/chemical engineers able to address this.
About Professor Nigel Brandon
Professor Nigel Brandon OBE FREng is an electrochemical engineer whose research interests are focussed on electrochemical devices for energy applications. He heads the Sustainable Gas Institute at Imperial College London, is Director of the Hydrogen and Fuel Cell Hub, Co-Director of the Energy SuperStore Hub, and founder of the UK fuel cell company Ceres Power.
Professor Chris Hardacre, HoS, University of Manchester
Non Thermal Activated Catalysis
This presentation will examine the use of non-thermal plasma activation of heterogeneous catalysts for gas phase reactions. Specifically, the use hybrid plasma-catalysis for deNOx, CH4 oxidation and low temperature water gas shift reactions will be shown using in-situ infra-red and x-ray absorption spectroscopy to understand the effect of the plasma on the catalyst structure, surface species and reaction mechanism.
About Professor Chris Hardacre
Chris Hardacre obtained his PhD from Cambridge University in 1994 and moved to Queen’s University, Belfast in 1995. In 2016 he moved to the University of Manchester where he is Head of the School of Chemical Engineering and Analytical Science. He is a Co-PI for the UK Catalysis Hub and has published over 370 papers, 9 patents and 6 book chapters.
Professor Steven Howdle, University of Nottingham
Green Polymers: Chemistry and Processing
The lecture will describe our development of new polymers from renewable resources and also the use of scCO2 to create new polymers and new polymeric materials, via sustainable routes, for applications from drug delivery through to paints and coatings.
About Professor Steven Howdle
Steve Howdle’s research focuses on sustainable chemistry and in particular on the utilisation of supercritical carbon dioxide for synthesising new polymers and for innovative polymer processing. He has published ~ 320 papers in this field and has commercialised his research through spin out company Critical Pharmaceuticals focussed upon using scCO2 to prepare polymeric drug delivery devices.
Professor Omar Matar, Imperial College
A Fundamental Approach to Modelling Multiphase Flows: Correlations No More
The ability to predict the behaviour of multiphase flows accurately, reliably, and efficiently addresses a major challenge of global economic, scientific, and societal importance. These flows are central to micro-fluidics, virtually every processing and manufacturing technology, oil-and-gas, nuclear, and biomedical applications. Significant advances have been made in the numerical procedures to simulate these flows; examples of these include the use of Large Eddy Simulations to simulate turbulence, and interface-capturing or tracking techniques to deal with the free surface. These codes have made progress in simulating the interaction of a turbulent flow field with an interface, however, there remains a large gap between what is achievable computationally and ‘real-life’ systems; the latter are beyond what can be addressed with current methods. As a result, the use of empirical correlations to bridge this gap remains the norm. We will present the latest on the modelling framework that we are currently developing as part of the Multi-scale Examination of MultiPHase physIcs in flowS (MEMPHIS) programme in order to minimise the use of correlations and shift towards the use of numerical simulations as a truly predictive tool that can be used as a sound basis for design. The framework features massively-parallelisable interface-capturing and front-tracking methods, 3D, adaptive, unstructured meshes, and sophisticated multi-scale, multi-physics models. Support from the Engineering & Physical Sciences Research Council, UK (grant no. EP/K003976/1) is gratefully acknowledged.
About Professor Omar Matar
Professor Omar Matar is a Professor in Fluid Mechanics in the Department of Chemical Engineering at Imperial College London. He is a Petronas/Royal Academy of Engineering Research Chair in Multiphase Fluid Dynamics, and a Fellow of the American Physical Society. He has co-authored over 200 refereed papers, 5000 citations, h-index of 42, and over 55 invited talks. He is the Editor-in-Chief of J. Eng. Math., and has received over £20m in funding from EPSRC and industry, including the £5m EPSRC Programme Grant ‘Multi-scale examination of multiphase physics in flows (MEMPHIS)’. He is also the Director of the Transient Multiphase Flow 18-company oil-and-gas consortium, and the Deputy Director of an EPSRC Centre for Doctoral Training in Fluid Dynamics across Scales.
Professor Nigel Titchener-Hooker, FREng, UCL
The Bioprocessing Challenges of Targeted Healthcare Manufacture
The past decades have seen biopharmaceuticals begin to dominate the drug development pathway and already we can see potent biologics bringing benefits to populations on a truly impressive scale. There remains much to do before we can claim however that the benefits of our burgeoning capabilities in the life sciences are fully translated into treatments, delivered globally. That challenge, of enabling the exquisite power of biologically-derived drugs and treatments to benefit world-wide populations, will require significant engineering innovation. This talk will look at some of these development and illustrate potential solutions driven by work from the Department of Biochemical Engineering at University College London (UCL); a pioneer in the field.
Challenges will be used to illustrate the nature of the advances made and of the path ahead. The first is the need to move rapidly from promising drug candidate to a robust and efficient process. Here UCL created the concept of ultra scale-down (USD) which can enable process insights to be gained with a few 10’s of mL of material.
Second is the need to make best decisions, be that at the level of technology choice or on a portfolio of drugs for development. So called Decisional Tools have been deployed to address such questions and to provide critical direction to research efforts as drugs move toward manufacture.
The talk will be supported with relevant industrial examples to demonstrate how our capacity to engineer global biological solutions continues to advance the translation of exciting life science into commercial outcomes.
About Professor Nigel Titchener-Hooker
Professor Nigel Titchener-Hooker, CENg, FIChemE, FREng is Dean of UCL Engineering and was for the past 7 years head of the Department of Biochemical Engineering. He directs the EPSRC Centre for Innovative Manufacturing of Emerging Macromolecular Therapies. This involves collaboration with an international consortium of 30 companies and is valued at over £45M. As the first director of the Engineering Doctorate Centre for Bioprocess Leadership he managed a portfolio of over 60 doctorate programmes with companies spanning the whole breadth of the biotech industry. His particular research interests are centred on the delivery of whole bioprocess solutions and in particular the interface between unit operations. He pioneered studies in the area of process-business decision making and as Director of the Innovative Manufacturing Research Centre (IMRC) in Bioprocessing was closely involved with the creation of ultra scale-down tools for the evolution of process flowsheets for the efficient recovery and purification of high value protein therapeutics. He pioneered the EPSRC Centre for Innovative manufacture of Emergent Macromolecular Therapies which was rated as outstanding in its international mid-term review.
Nigel has held consultancies with a broad range of international companies and serves on the editorial board of key journals. Elected a Fellow of the Royal Academy of Engineering in 2008 in recognition of his pioneering work on biopharmaceuticals manufacturing he is also a Fellow of the Institution of Chemical Engineers. He was the first non-USA Chair of the Board of the prestigious Recovery of Biological Products conference series. He was selected to the EPSRC Strategic Advisory Network reporting direct to Council. In 2013 he was awarded the Donald Medal by the Institution of Chemical Engineers in recognition of his contributions to the discipline and led the Department to win a Queens Anniversary Trust Award for its pioneering studies underpinning the bioprocessing industry in 2014. He was awarded the prestigious Danckwerts Medal by the AIChE and the IChemE also in 2014. In 2016 the BIA honoured him with the Peter Dunnill Award in recognition ofhis life-time contributions to the sector.
Professor David York, FREng, University of Leeds
The Engineering of Formulated Products
The traditional role of the chemical engineer is someone who designs and develops the processes that make a diverse range of chemicals at full scale based on their expertise in unit operations, chemical reaction equilibrium and kinetics and scale up. In doing so they have to take into consideration health and safety and cost issues.
Formulated products, however are purchased by customers for their functionality rather than their chemistry. This functionality can be achieved by a variety of different chemical components. In addition a key property that influences functionality is the physical structure of the product. This structure is heavily dependent on the process conditions as much as the material properties of the components. Indeed engineering such structures by physical processes are not only cheaper but also allow structures that cannot be achieved by chemistry manipulation alone.
The skills to do this are part of the chemical engineer’s toolbox with their knowledge of heat and mass transfer, chemistry, scale up and the ability to create mathematical models. Thus this talk will discuss the importance of the chemical engineer being involved in the design of formulated products at the very start, and even in understanding the usage process to develop cost effective and customer preferred products.
About Professor David York
David York holds the chair of Structured Particulate Materials at Leeds after 35 years as a research engineer at Procter and Gamble. There he developed processes for the synthesis of novel formulated products from bench to plant start up and led a team of engineers looking into novel technologies to radically change the market, one of which led to the multi billion business involving water soluble unit dose products.
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